A Constitutively Active Variant of the Quorum-Sensing Regulator LuxO Affects Protease Production and Biofilm Formation in Vibrio cholerae

Vibrio cholerae normally inhabits aquatic habitats but can cause a severe diarrheal illness in humans. Its arsenal of virulence factors includes a secreted hemagglutinin (HA) protease. An HA protease-deficient mutant of V. cholerae was isolated and designated E7946 mpc. E7946 mpc was found to contai...

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Bibliografiske detaljer
Main Authors: Vance, Russell E., Zhu, Jun, Mekalanos, John J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC153284/
https://ncbi.nlm.nih.gov/pubmed/12704130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.5.2571-2576.2003
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