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Deletion of the Aspergillus fumigatus Gene Encoding the Ras-Related Protein RhbA Reduces Virulence in a Model of Invasive Pulmonary Aspergillosis

Aspergillus fumigatus is the predominant mold pathogen in patients who lack functional innate immunity. The A. fumigatus rhbA gene was first identified as a transcript that was upregulated when the organism was grown in the presence of mammalian cells. To gain insight into the function of rhbA in th...

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Autors principals: Panepinto, John C., Oliver, Brian G., Fortwendel, Jarrod R., Smith, Darcey L. H., Askew, David S., Rhodes, Judith C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC153280/
https://ncbi.nlm.nih.gov/pubmed/12704156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.5.2819-2826.2003
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