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Deletion of the Aspergillus fumigatus Gene Encoding the Ras-Related Protein RhbA Reduces Virulence in a Model of Invasive Pulmonary Aspergillosis

Aspergillus fumigatus is the predominant mold pathogen in patients who lack functional innate immunity. The A. fumigatus rhbA gene was first identified as a transcript that was upregulated when the organism was grown in the presence of mammalian cells. To gain insight into the function of rhbA in th...

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Vydáno v:Infect Immun
Hlavní autoři: Panepinto, John C., Oliver, Brian G., Fortwendel, Jarrod R., Smith, Darcey L. H., Askew, David S., Rhodes, Judith C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2003
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On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153280/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12704156/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.5.2819-2826.2003
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