Immunization with Genetic Toxoids of the Arcanobacterium pyogenes Cholesterol-Dependent Cytolysin, Pyolysin, Protects Mice against Infection

Pyolysin (PLO), a cholesterol-dependent cytolysin expressed by Arcanobacterium pyogenes, is an important host-protective antigen. However, this molecule is toxic and requires inactivation prior to its use as a vaccine. Three genetically toxoided, nonhemolytic PLO molecules, HIS-PLO.F(497), HIS-PLO.Δ...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Jost, B. Helen, Trinh, Hien T., Songer, J. Glenn, Billington, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Molecular Pathogenesis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC153263/
https://ncbi.nlm.nih.gov/pubmed/12704180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.5.2966-2969.2003
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares