Immunization with cDNA Expressed by Amastigotes of Trypanosoma cruzi Elicits Protective Immune Response against Experimental Infection

Immunization of mice with plasmids containing Trypanosoma cruzi genes induced specific antibodies, CD4(+) Th1 and CD8(+) Tc1 cells, and protective immunity against infection. In most cases, plasmids used for DNA vaccination contained genes encoding antigens expressed by trypomastigotes, the nonrepli...

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Autores principales: Boscardin, Silvia B., Kinoshita, Sheila S., Fujimura, Adriana E., Rodrigues, Mauricio M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Fungal and Parasitic Infections
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC153249/
https://ncbi.nlm.nih.gov/pubmed/12704149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.5.2744-2757.2003
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