Immunization with cDNA Expressed by Amastigotes of Trypanosoma cruzi Elicits Protective Immune Response against Experimental Infection

Immunization of mice with plasmids containing Trypanosoma cruzi genes induced specific antibodies, CD4(+) Th1 and CD8(+) Tc1 cells, and protective immunity against infection. In most cases, plasmids used for DNA vaccination contained genes encoding antigens expressed by trypomastigotes, the nonrepli...

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Publié dans:	Infect Immun
Auteurs principaux:	Boscardin, Silvia B., Kinoshita, Sheila S., Fujimura, Adriana E., Rodrigues, Mauricio M.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2003
Sujets:	Fungal and Parasitic Infections
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153249/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12704149/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.5.2744-2757.2003
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