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Structural and Functional Analysis of Mutations along the Crystallographic Dimer Interface of the Yeast TATA Binding Protein

The TATA binding protein (TBP) is a central component of the eukaryotic transcription machinery and is subjected to both positive and negative regulation. As is evident from structural and functional studies, TBP's concave DNA binding surface is inhibited by a number of potential mechanisms, in...

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Autori principali: Kou, Haiping, Irvin, Jordan D., Huisinga, Kathryn L., Mitra, Madhusmita, Pugh, B. Franklin
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC153203/
https://ncbi.nlm.nih.gov/pubmed/12697819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.9.3186-3201.2003
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