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Structural and Functional Analysis of Mutations along the Crystallographic Dimer Interface of the Yeast TATA Binding Protein

The TATA binding protein (TBP) is a central component of the eukaryotic transcription machinery and is subjected to both positive and negative regulation. As is evident from structural and functional studies, TBP's concave DNA binding surface is inhibited by a number of potential mechanisms, in...

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Библиографические подробности
Главные авторы: Kou, Haiping, Irvin, Jordan D., Huisinga, Kathryn L., Mitra, Madhusmita, Pugh, B. Franklin
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2003
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC153203/
https://ncbi.nlm.nih.gov/pubmed/12697819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.9.3186-3201.2003
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