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Dimerization of MLH1 and PMS2 Limits Nuclear Localization of MutLα

DNA mismatch repair maintains genomic stability by detecting and correcting mispaired DNA sequences and by signaling cell death when DNA repair fails. The mechanism by which mismatch repair coordinates DNA damage and repair with cell survival or death is not understood, but it suggests the need for...

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Autors principals: Wu, Xiaosheng, Platt, Jeffrey L., Cascalho, Marilia
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC153201/
https://ncbi.nlm.nih.gov/pubmed/12697830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.9.3320-3328.2003
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