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Dimerization of MLH1 and PMS2 Limits Nuclear Localization of MutLα

DNA mismatch repair maintains genomic stability by detecting and correcting mispaired DNA sequences and by signaling cell death when DNA repair fails. The mechanism by which mismatch repair coordinates DNA damage and repair with cell survival or death is not understood, but it suggests the need for...

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Pubblicato in:Mol Cell Biol
Autori principali: Wu, Xiaosheng, Platt, Jeffrey L., Cascalho, Marilia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2003
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153201/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12697830/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.9.3320-3328.2003
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