MXI1-0, an Alternatively Transcribed Mxi1 Isoform, Is Overexpressed in Glioblastomas

The c-Myc transcription factor regulates expression of genes related to cell growth, division, and apoptosis. Mxi1, a member of the Mad family, represses transcription of c-Myc-regulated genes by mediating chromatin condensation via histone deacetylase and the Sin3 corepressor. Mxi1 is a c-Myc antag...

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Autori principali: Engstrom, Lars D, Youkilis, Andrew S, Gorelick, Judith L, Zheng, Datong, Ackley, Valerie, Petroff, Christy A, Benson, Linda Q, Coon, Melissa R, Zhu, Xiaoxiang, Hanash, Samir M, Wechsler, Daniel S
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press Inc. 2004
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1531670/
https://ncbi.nlm.nih.gov/pubmed/15548375
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