N-Myc Differentially Regulates Expression of MXI1 Isoforms in Neuroblastoma

Amplification of the MYCN proto-oncogene is associated with a poor prognosis in patients with metastatic neuroblastoma (NB). MYCN encodes the N-Myc protein, a transcriptional regulator that dimerizes with the Max transcription factor, binds to E-box DNA sequences, and regulates genes involved in cel...

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Bibliographic Details
Main Authors: Armstrong, Michael B, Mody, Rajen J, Ellis, D Christian, Hill, Adam B, Erichsen, David A, Wechsler, Daniel S
Format: Artigo
Language:Inglês
Published: Neoplasia Press Inc. 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884527/
https://ncbi.nlm.nih.gov/pubmed/24403858
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