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Selective Loss of Codon 72 Proline p53 and Frequent Mutational Inactivation of the Retained Arginine Allele in Colorectal Cancer

According to recent reports, some cancer types exhibit nonrandom allele loss at codon 72 in exon 4 of the p53 gene [coding for proline (72Pro) or arginine (72Arg)]. To clarify this phenomenon for colorectal cancer and to find out if this preferential loss might have any functional significance, p53...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Schneider-Stock, Regine, Boltze, Carsten, Peters, Brigitte, Szibor, Reinhard, Landt, Olfert, Meyer, Frank, Roessner, Albert
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Neoplasia Press Inc. 2004
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1531656/
https://ncbi.nlm.nih.gov/pubmed/15548361
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