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Endosomal Dynamics of Met Determine Signaling Output
Proteasomal activity is required for Met receptor degradation after acute stimulation with hepatocyte growth factor (HGF). Inhibition of proteasomal activity with lactacystin leads to a block in the endocytic trafficking of Met such that the receptor fails to reach late endosomes/lysosomes, where de...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Cell Biology
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC153105/ https://ncbi.nlm.nih.gov/pubmed/12686592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-09-0578 |
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