Distinct roles of dopamine D2L and D2S receptor isoforms in the regulation of protein phosphorylation at presynaptic and postsynaptic sites

Dopamine D2 receptors are highly expressed in the dorsal striatum where they participate in the regulation of (i) tyrosine hydroxylase (TH), in nigrostriatal nerve terminals, and (ii) the dopamine- and cAMP-regulated phosphoprotein of 32 kDa (DARPP-32), in medium spiny neurons. Two isoforms of the D...

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Detalhes bibliográficos
Main Authors: Lindgren, Niklas, Usiello, Alessandro, Goiny, Michel, Haycock, John, Erbs, Eric, Greengard, Paul, Hökfelt, Tomas, Borrelli, Emiliana, Fisone, Gilberto
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC153088/
https://ncbi.nlm.nih.gov/pubmed/12651945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0730708100
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