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Regulation of hepatic fasting response by PPARγ coactivator-1α (PGC-1): Requirement for hepatocyte nuclear factor 4α in gluconeogenesis

The liver plays several critical roles in the metabolic adaptation to fasting. We have shown previously that the transcriptional coactivator peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) is induced in fasted or diabetic liver and activates the entire program of gluconeogenesis...

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Detalhes bibliográficos
Main Authors: Rhee, James, Inoue, Yusuke, Yoon, J. Cliff, Puigserver, Pere, Fan, Melina, Gonzalez, Frank J., Spiegelman, Bruce M.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC153039/
https://ncbi.nlm.nih.gov/pubmed/12651943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0730870100
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