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Domain organization of the type 1 inositol 1,4,5-trisphosphate receptor as revealed by single-particle analysis

The inositol 1,4,5-trisphosphate receptor (IP(3)R) is a tetrameric intracellular Ca(2+) channel, which mediates the release of Ca(2+) from the endoplasmic reticulum in response to many different extracellular stimuli. We present a 3D structure of the type 1 IP(3)R obtained by electron microscopy and...

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Detalhes bibliográficos
Main Authors: da Fonseca, Paula C. A., Morris, Stephen A., Nerou, Edmund P., Taylor, Colin W., Morris, Edward P.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC153026/
https://ncbi.nlm.nih.gov/pubmed/12651956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0536251100
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