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The role of disulfide bonds in the assembly and function of MD-2
MD-2 is a secreted glycoprotein that binds to the extracellular domain of Toll-like receptor 4 (TLR4) and is required for the activation of TLR4 by lipopolysaccharide (LPS). The protein contains seven Cys residues and consists of a heterogeneous collection of disulfide-linked oligomers. To investiga...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The National Academy of Sciences
2003
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC153023/ https://ncbi.nlm.nih.gov/pubmed/12642668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0630495100 |
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