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Insight into the mechanism of aromatic hydroxylation by toluene 4-monooxygenase by use of specifically deuterated toluene and p-xylene

The present studies address the mechanism of aromatic hydroxylation used by the natural and G103L isoforms of the diiron enzyme toluene 4-monooxygenase. These isoforms have comparable catalytic parameters but distinct regiospecificities for toluene hydroxylation. Hydroxylation of ring-deuterated p-x...

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Библиографические подробности
Главные авторы: Mitchell, Kevin H., Rogge, Corina E., Gierahn, Todd, Fox, Brian G.
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 2003
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC152999/
https://ncbi.nlm.nih.gov/pubmed/12640145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0636619100
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