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Electrochemical and NMR spectroscopic studies of distal pocket mutants of nitrophorin 2: Stability, structure, and dynamics of axial ligand complexes

WT and leucine → valine distal pocket mutants of nitrophorin 2 (NP2) and their NO complexes have been investigated by spectroelectrochemistry. NO complexes of two of the mutants exhibit more positive reduction potential shifts than does the WT protein, thus indicating stabilization of the Fe(II)–NO...

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Autors principals: Shokhireva, Tatjana Kh., Berry, Robert E., Uno, Elizabeth, Balfour, Celia A., Zhang, Hongjun, Walker, F. Ann
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC152998/
https://ncbi.nlm.nih.gov/pubmed/12642672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0536641100
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