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Interdomain zinc site on human albumin

Albumin is the major transport protein in blood for Zn(2+), a metal ion required for physiological processes and recruited by various drugs and toxins. However, the Zn(2+)-binding site(s) on albumin is ill-defined. We have analyzed the 18 x-ray crystal structures of human albumin in the PDB and iden...

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Bibliografiske detaljer
Main Authors: Stewart, Alan J., Blindauer, Claudia A., Berezenko, Stephen, Sleep, Darrell, Sadler, Peter J.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC152985/
https://ncbi.nlm.nih.gov/pubmed/12598656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0436576100
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