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pH-Dependent Protein Binding Properties of Uremic Toxins In Vitro

Protein-bound uremic toxins (PBUTs) are difficult to remove using conventional dialysis treatment owing to their high protein-binding affinity. As pH changes the conformation of proteins, it may be associated with the binding of uremic toxins. Albumin conformation at pH 2 to 13 was analyzed using ci...

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Principais autores: Suguru Yamamoto, Kenichi Sasahara, Mio Domon, Keiichi Yamaguchi, Toru Ito, Shin Goto, Yuji Goto, Ichiei Narita
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2021-02-01
סדרה:Toxins
נושאים:
pH
uremic toxins
albumin
indoxyl sulfate
isothermal titration calorimetry
גישה מקוונת:https://www.mdpi.com/2072-6651/13/2/116
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