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Impacts of Indoxyl Sulfate and p-Cresol Sulfate on Chronic Kidney Disease and Mitigating Effects of AST-120

Uremic toxins, such as indoxyl sulfate (IS) and p-cresol, or p-cresyl sulfate (PCS), are markedly accumulated in the organs of chronic kidney disease (CKD) patients. These toxins can induce inflammatory reactions and enhance oxidative stress, prompting glomerular sclerosis and interstitial fibrosis,...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Wen-Chih Liu, Yasuhiko Tomino, Kuo-Cheng Lu
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2018-09-01
Schriftenreihe:Toxins
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Online-Zugang:http://www.mdpi.com/2072-6651/10/9/367
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