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The role of copper and protons in heme-copper oxidases: Kinetic study of an engineered heme-copper center in myoglobin

To probe the role of copper and protons in heme-copper oxidase (HCO), we have performed kinetic studies on an engineered heme-copper center in sperm whale myoglobin (Leu-29 → His/Phe-43 → His, called Cu(B)Mb) that closely mimics the heme-copper center in HCO. In the absence of metal ions, the engine...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Sigman, Jeffrey A., Kim, Hyeon K., Zhao, Xuan, Carey, James R., Lu, Yi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2003
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Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152973/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12655052/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0737308100
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