Chemokine receptor mutant CX3CR1-M280 has impaired adhesive function and correlates with protection from cardiovascular disease in humans

The chemokine receptor CX3CR1 is a proinflammatory leukocyte receptor specific for the chemokine fractalkine (FKN or CX3CL1). In two retrospective studies, CX3CR1 has been implicated in the pathogenesis of atherosclerotic cardiovascular disease (CVD) based on statistical association of a common rece...

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Vydáno v:	J Clin Invest
Hlavní autoři:	McDermott, David H., Fong, Alan M., Yang, Qiong, Sechler, Joan M., Cupples, L. Adrienne, Merrell, Maya N., Wilson, Peter W.F., D’Agostino, Ralph B., O’Donnell, Christopher J., Patel, Dhavalkumar D., Murphy, Philip M.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 2003
Témata:	Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152935/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12697743/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI16790
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