Chemokine receptor mutant CX3CR1-M280 has impaired adhesive function and correlates with protection from cardiovascular disease in humans

The chemokine receptor CX3CR1 is a proinflammatory leukocyte receptor specific for the chemokine fractalkine (FKN or CX3CL1). In two retrospective studies, CX3CR1 has been implicated in the pathogenesis of atherosclerotic cardiovascular disease (CVD) based on statistical association of a common rece...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	McDermott, David H., Fong, Alan M., Yang, Qiong, Sechler, Joan M., Cupples, L. Adrienne, Merrell, Maya N., Wilson, Peter W.F., D’Agostino, Ralph B., O’Donnell, Christopher J., Patel, Dhavalkumar D., Murphy, Philip M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 2003
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152935/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12697743/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI16790
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