Determinants of proteasome recognition of ornithine decarboxylase, a ubiquitin-independent substrate

Ornithine decarboxylase (ODC) is regulated by its metabolic products through a feedback loop that employs a second protein, antizyme 1 (AZ1). AZ1 accelerates the degradation of ODC by the proteasome. We used purified components to study the structural elements required for proteasomal recognition of...

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Pubblicato in:	EMBO J
Autori principali:	Zhang, Mingsheng, Pickart, Cecile M., Coffino, Philip
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2003
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152902/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12660156/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg158
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