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Rap1p telomere association is not required for mitotic stability of a C(3)TA(2) telomere in yeast

Telomeric DNA usually consists of a repetitive sequence: C(1–3)A/TG(1–3) in yeast, and C(3)TA(2)/T(2)AG(3) in vertebrates. In yeast, the sequence-specific DNA- binding protein Rap1p is thought to be essential for telomere function. In a tlc1h mutant, the templating region of the telomerase RNA gene...

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Autors principals: Alexander, Mary Kate, Zakian, Virginia A.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC152898/
https://ncbi.nlm.nih.gov/pubmed/12660174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg154
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