Thyroid hormone-regulated enhancer blocking: cooperation of CTCF and thyroid hormone receptor

The highly conserved, ubiquitously expressed, zinc finger protein CTCF is involved in enhancer blocking, a mechanism crucial for shielding genes from illegitimate enhancer effects. Interestingly, CTCF-binding sites are often flanked by thyroid hormone response elements (TREs), as at the chicken lyso...

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Main Authors: Lutz, Marcus, Burke, Les J., LeFevre, Pascal, Myers, Fiona A., Thorne, Alan W., Crane-Robinson, Colyn, Bonifer, Constanze, Filippova, Galina N., Lobanenkov, Victor, Renkawitz, Rainer
Format: Artigo
Language:Inglês
Published: Oxford University Press 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC152892/
https://ncbi.nlm.nih.gov/pubmed/12660164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg147
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