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Thyroid hormone-regulated enhancer blocking: cooperation of CTCF and thyroid hormone receptor
The highly conserved, ubiquitously expressed, zinc finger protein CTCF is involved in enhancer blocking, a mechanism crucial for shielding genes from illegitimate enhancer effects. Interestingly, CTCF-binding sites are often flanked by thyroid hormone response elements (TREs), as at the chicken lyso...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC152892/ https://ncbi.nlm.nih.gov/pubmed/12660164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg147 |
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