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Elucidation of substrate binding interactions in a membrane transport protein by mass spectrometry
Integration of biochemical and biophysical data on the lactose permease of Escherichia coli has culminated in a molecular model that predicts substrate–protein proximities which include interaction of a hydroxyl group in the galactopyranosyl ring with Glu269. In order to test this hypothesis, we stu...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC152890/ https://ncbi.nlm.nih.gov/pubmed/12660154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg145 |
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