Glutamate at the phosphorylation site of response regulator CtrA provides essential activities without increasing DNA binding
The essential response regulator CtrA controls the Caulobacter crescentus cell cycle and phosphorylated CtrA∼P preferentially binds target DNA in vitro. The CtrA aspartate to glutamate (D51E) mutation mimics phosphorylated CtrA∼P in vivo and rescues non-viable C.crescentus cells. However, we observe...
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| Yayımlandı: | Nucleic Acids Res |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2003
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152873/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12626719/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg271 |
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