Bypassing antibiotic selection: positive screening of genetically modified cells with an antigen-dependent proliferation switch

While antibiotic selection has been routinely used for the selection of genetically modified cells, administration of cytotoxic drugs often leads to deleterious effects not only to inert cells but also to transfected or transduced ones. In this study, we propose an Antigen-MEdiated Genetically modif...

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Bibliographic Details
Main Authors: Kawahara, Masahiro, Ueda, Hiroshi, Morita, Sumiyo, Tsumoto, Kouhei, Kumagai, Izumi, Nagamune, Teruyuki
Format: Artigo
Language:Inglês
Published: Oxford University Press 2003
Subjects:
NAR Methods Online
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC152817/
https://ncbi.nlm.nih.gov/pubmed/12655020
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