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Bypassing antibiotic selection: positive screening of genetically modified cells with an antigen-dependent proliferation switch

While antibiotic selection has been routinely used for the selection of genetically modified cells, administration of cytotoxic drugs often leads to deleterious effects not only to inert cells but also to transfected or transduced ones. In this study, we propose an Antigen-MEdiated Genetically modif...

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Hlavní autoři: Kawahara, Masahiro, Ueda, Hiroshi, Morita, Sumiyo, Tsumoto, Kouhei, Kumagai, Izumi, Nagamune, Teruyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC152817/
https://ncbi.nlm.nih.gov/pubmed/12655020
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