Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: higher frequency of the risk allele in male compared to female patients

The functional single-nucleotide polymorphism (SNP) of the gene PTPN22 is a susceptibility locus for rheumatoid arthritis (RA). The study presented here describes the association of the PTPN22 1858T allele with RA in a German patient cohort; 390 patients with RA and 349 controls were enrolled in the...

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Autors principals: Pierer, Matthias, Kaltenhäuser, Sylke, Arnold, Sybille, Wahle, Matthias, Baerwald, Christoph, Häntzschel, Holm, Wagner, Ulf
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2006
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1526616/
https://ncbi.nlm.nih.gov/pubmed/16635271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1945
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