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B lymphocytopenia in rheumatoid arthritis is associated with the DRB1 shared epitope and increased acute phase response

The influence of HLA DRB1 alleles on B-cell homeostasis was analyzed in 164 patients with rheumatoid arthritis (RA). The percentages of CD19(+) B lymphocytes determined in the peripheral circulation of 94 retrospectively recruited RA patients followed a bimodal distribution. Two frequency peaks (B-c...

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Detalhes bibliográficos
Main Authors: Wagner, Ulf, Kaltenhäuser, Sylke, Pierer, Matthias, Wilke, Bernd, Arnold, Sybille, Häntzschel, Holm
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125293/
https://ncbi.nlm.nih.gov/pubmed/12106500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar420
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