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NPAT Expression Is Regulated by E2F and Is Essential for Cell Cycle Progression

NPAT is an in vivo substrate of cyclin E-Cdk2 kinase and is thought to play a critical role in coordinated transcriptional activation of histone genes during the G(1)/S-phase transition and in S-phase entry in mammalian cells. Here we show that NPAT transcription is up-regulated at the G(1)/S-phase...

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Enregistré dans:
Publié dans:Mol Cell Biol
Auteurs principaux: Gao, Guang, Bracken, Adrian P., Burkard, Karina, Pasini, Diego, Classon, Marie, Attwooll, Claire, Sagara, Masashi, Imai, Takashi, Helin, Kristian, Zhao, Jiyong
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2003
Sujets:
Cell Growth and Development
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152552/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12665581/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.8.2821-2833.2003
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