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Temporal and spatial delineation of mouse Otx2 functions by conditional self-knockout
To identify the independent spatial and temporal activities of the essential developmental gene the Otx2, the germline mutation of which is lethal at embryonic day 8.5, we floxed one allele and substituted the other with an inducible CreER recombinase gene. This makes ‘trans' self-knockout poss...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1525150/ https://ncbi.nlm.nih.gov/pubmed/16845372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400751 |
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