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Otx2 ChIP-seq Reveals Unique and Redundant Functions in the Mature Mouse Retina

During mouse retinal development and into adulthood, the transcription factor Otx2 is expressed in pigment epithelium, photoreceptors and bipolar cells. In the mature retina, Otx2 ablation causes photoreceptor degeneration through a non-cell-autonomous mechanism involving Otx2 function in the suppor...

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Detalhes bibliográficos
Main Authors: Samuel, Alexander, Housset, Michael, Fant, Bruno, Lamonerie, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928427/
https://ncbi.nlm.nih.gov/pubmed/24558479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089110
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