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Influence of simulated microgravity on the activation of the small GTPase Rho involved in cytoskeletal formation – molecular cloning and sequencing of bovine leukemia-associated guanine nucleotide exchange factor

BACKGROUND: The irregular formation of cytoskeletal fibers in spaceflown experimental cells has been observed, but the disorganization process of fibers is still poorly understood. It is well known that the activation of the small GTPase Rho leads to actin stress fibers assembly. This study was perf...

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Main Authors: Higashibata, Akira, Imamizo-Sato, Mari, Seki, Masaya, Yamazaki, Takashi, Ishioka, Noriaki
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1524780/
https://ncbi.nlm.nih.gov/pubmed/16803636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-7-19
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