Efficacy and tolerability of gemtuzumab ozogamicin (anti-CD33 monoclonal antibody, CMA-676, Mylotarg(®)) in children with relapsed/refractory myeloid leukemia

BACKGROUND: Gemtuzumab ozogamicin (GO) is a cytotoxic anti-CD33 monoclonal antibody that has given promising preliminary results in adult myeloid CD33+ AML. We conducted a retrospective multicenter study of 12 children treated with GO on a compassionate basis (median age 5.5 y). Three patients (2 MD...

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Bibliographic Details
Main Authors: Brethon, Benoit, Auvrignon, Anne, Galambrun, Claire, Yakouben, Karima, Leblanc, Thierry, Bertrand, Yves, Leverger, Guy, Baruchel, André
Format: Artigo
Language:Inglês
Published: BioMed Central 2006
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1523361/
https://ncbi.nlm.nih.gov/pubmed/16805911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-6-172
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