Contribution of alpha- and beta-defensins to lung function decline and infection in smokers: an association study

BACKGROUND: Alpha-defensins, which are major constituents of neutrophil azurophilic granules, and beta-defensins, which are expressed in airway epithelial cells, could contribute to the pathogenesis of chronic obstructive pulmonary disease by amplifying cigarette smoke-induced and infection-induced...

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Detalhes bibliográficos
Main Authors: Wallace, Alison M, He, Jian-Qing, Burkett, Kelly M, Ruan, Jian, Connett, John E, Anthonisen, Nicholas R, Paré, Peter D, Sandford, Andrew J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1523340/
https://ncbi.nlm.nih.gov/pubmed/16700921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-7-76
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