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Verification of predicted alternatively spliced Wnt genes reveals two new splice variants (CTNNB1 and LRP5) and altered Axin-1 expression during tumour progression

BACKGROUND: Splicing processes might play a major role in carcinogenesis and tumour progression. The Wnt pathway is of crucial relevance for cancer progression. Therefore we focussed on the Wnt/β-catenin signalling pathway in order to validate the expression of sequences predicted as alternatively s...

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Bibliografiske detaljer
Main Authors: Pospisil, Heike, Herrmann, Alexander, Butherus, Kristine, Pirson, Stefan, Reich, Jens G, Kemmner, Wolfgang
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1523213/
https://ncbi.nlm.nih.gov/pubmed/16772034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-7-148
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