Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif

Upon recognition of viral infection, RIG-I and Helicard recruit a newly identified adapter termed Cardif, which induces type I interferon (IFN)-mediated antiviral responses through an unknown mechanism. Here, we demonstrate that TRAF3, like Cardif, is required for type I interferon production in res...

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Bibliographische Detailangaben
Hauptverfasser: Saha, Supriya K, Pietras, Eric M, He, Jeannie Q, Kang, Jason R, Liu, Su-Yang, Oganesyan, Gagik, Shahangian, Arash, Zarnegar, Brian, Shiba, Travis L, Wang, Yao, Cheng, Genhong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1523175/
https://ncbi.nlm.nih.gov/pubmed/16858409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601220
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