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Acetylation and MAPK phosphorylation cooperate to regulate the degradation of active GATA-1

Regulation of transcription requires mechanisms to both activate and terminate transcription factor activity. GATA-1 is a key haemopoietic transcription factor whose activity is increased by acetylation. We show here that acetylated GATA-1 is targeted for degradation via the ubiquitin/proteasome pat...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hernandez-Hernandez, Angel, Ray, Pampa, Litos, Gabi, Ciro, Marco, Ottolenghi, Sergio, Beug, Hartmut, Boyes, Joan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1523174/
https://ncbi.nlm.nih.gov/pubmed/16858405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601228
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