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Acetylation and MAPK phosphorylation cooperate to regulate the degradation of active GATA-1
Regulation of transcription requires mechanisms to both activate and terminate transcription factor activity. GATA-1 is a key haemopoietic transcription factor whose activity is increased by acetylation. We show here that acetylated GATA-1 is targeted for degradation via the ubiquitin/proteasome pat...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1523174/ https://ncbi.nlm.nih.gov/pubmed/16858405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601228 |
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