Gene–environment interaction modulated by allelic heterogeneity in inflammatory diseases

CARD15 is a major susceptibility gene for a frequent multifactorial chronic inflammatory bowel disorder, Crohn disease (CD). By using NF-κB activation assays, the cytosolic CARD15 was shown to efficiently detect bacterial peptidoglycan (PGN), reminiscent of the PGN recognition protein surveillance m...

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Detalhes bibliográficos
Main Authors: Chamaillard, Mathias, Philpott, Dana, Girardin, Stephen E., Zouali, Habib, Lesage, Suzanne, Chareyre, Fabrice, Bui, The Hung, Giovannini, Marco, Zaehringer, Ulrich, Penard-Lacronique, Virginie, Sansonetti, Philippe J., Hugot, Jean-Pierre, Thomas, Gilles
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC152314/
https://ncbi.nlm.nih.gov/pubmed/12626759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0530276100
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