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Senescence-specific gene expression fingerprints reveal cell-type-dependent physical clustering of up-regulated chromosomal loci

Replicative senescence is the state of irreversible proliferative arrest that occurs as a concomitant of progressive telomere shortening. By using cDNA microarrays and the gabriel system of computer programs to apply domain-specific and procedural knowledge for data analysis, we investigated global...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Hong, Pan, Kuang-Hung, Cohen, Stanley N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC152278/
https://ncbi.nlm.nih.gov/pubmed/12626749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2627983100
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