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Watching proteins fold one molecule at a time

Recent theoretical work suggests that protein folding involves an ensemble of pathways on a rugged energy landscape. We provide direct evidence for heterogeneous folding pathways from single-molecule studies, facilitated by a recently developed immobilization technique. Individual fluorophore-labele...

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Bibliografski detalji
Glavni autori: Rhoades, Elizabeth, Gussakovsky, Eugene, Haran, Gilad
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2003
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC152269/
https://ncbi.nlm.nih.gov/pubmed/12612345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2628068100
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