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Watching proteins fold one molecule at a time
Recent theoretical work suggests that protein folding involves an ensemble of pathways on a rugged energy landscape. We provide direct evidence for heterogeneous folding pathways from single-molecule studies, facilitated by a recently developed immobilization technique. Individual fluorophore-labele...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The National Academy of Sciences
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC152269/ https://ncbi.nlm.nih.gov/pubmed/12612345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2628068100 |
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