Mutations that affect the ability of the vnd/NK-2 homeoprotein to regulate gene expression: Transgenic alterations and tertiary structure

The importance in downstream target regulation of tertiary structure and DNA binding specificity of the protein encoded by the vnd/NK-2 homeobox gene is analyzed. The ectopic expression patterns of WT and four mutant vnd/NK-2 genes are analyzed together with expression of two downstream target genes...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Koizumi, Keita, Lintas, Carla, Nirenberg, Marshall, Maeng, Jin-Soo, Ju, Jeong-Ho, Mack, James W., Gruschus, James M., Odenwald, Ward F., Ferretti, James A.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 2003
Témata:	Biological Sciences
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152256/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12626758/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0438043100
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