Murine Coronavirus-Induced Hepatitis: JHM Genetic Background Eliminates A59 Spike-Determined Hepatotropism

Recombinant murine coronaviruses, differing only in the spike gene and containing the strain A59 (moderately hepatotropic) and JHM (neurotropic) spike genes in the background of the JHM genome, were compared for the ability to replicate in the liver and induce hepatitis in weanling C57BL/6 mice. Int...

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Pubblicato in:	J Virol
Autori principali:	Navas, Sonia, Weiss, Susan R.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Pathogenesis and Immunity
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152168/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12663803/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.8.4972-4978.2003
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